MAP65-1/PRC1 reinforces microtubules through nucleation
Mariana Romeiro Motta, Constantin Grisam, Mona Grünewald, Belinda König, Laura M. Meißner, Lukas Niese, Stefan Diez, Olivier Hamant, Laura Schaedel
The paper shows MAP65-1/PRC1 promotes microtubule nucleation on damaged lattices under mechanical stress, stabilizing microtubules and reinforcing their alignment with stress.
bioRxiv · Sep 14, 2025 · PreprintCell Biology