Cancer BiologyClinical EpigeneticsPeer-reviewed
Hypoxia alters the effects of hypomethylating agents in acute myeloid leukaemia cells.
Sam Humphries, Sean M. Burnard, Courtney D. Eggins…·Heather J Lee
This study shows hypoxia reduces the effectiveness of hypomethylating agents in AML cells by altering DNA methylation and antigen presentation pathways.
DOI 10.1186/s13148-025-01812-4