Monocytes are biological sensors of aging and frailty in humans
Chanhong Min, Charles Ezenwanne, Yoseph W. Dance, Nicolas C. Macaluso, Ladaisha T. Thompson, Lolita S. Nidadavolu, Akhil Katuri, Crystal Szczesny, Jacqueline M. Langdon, Edward J. Pearce, Peter M. Abadir, Jeremy D Walston, Jude M. Phillip
This study shows that monocyte behaviors can predict aging and frailty in humans using single-cell analysis and a deep learning model.
bioRxiv · Mar 12, 2026 · PreprintBioengineering