Large-pore connexin hemichannels function as molecule transporters independently of ion conduction
Pablo S. Gaete, Deepak Kumar, Cynthia I. Fernandez, Juan Manuel Valdez Capuccino, Aashish Bhatt, Wenjuan Jiang, Yi‐Chun Lin, Yu Liu, Andrew L. Harris, Y. L. Luo, Jorge E. Contreras
The paper shows that connexin hemichannels can transport molecules independently of ion conduction, challenging the conventional view of their function.
Proceedings of the National Academy of Sciences · Aug 8, 2024Peer-reviewedBiophysics