Pablo S. Gaete

This study shows that reducing S-nitrosylation of Cx43 in DMD mice prevents arrhythmias and myocardial injury under cardiac stress.

This study shows TRPV4 activation modulates endothelial Cx43 hemichannels via S-nitrosylation, influencing Ca2+ levels and vasomotor tone in resistance arteries.

The paper shows that connexin hemichannels can transport molecules independently of ion conduction, challenging the conventional view of their function.