Wenjuan Jiang

A two-step clockwork mechanism opens a proteo-lipidic pore in PIEZO2 channels

This study reveals how tension-induced structural changes in PIEZO2 channels lead to pore opening and ion conduction through dynamic conformational motions.

Mammalian PIEZO channels rectify anionic currents

This study shows that mammalian PIEZO1 and PIEZO2 channels rectify chloride currents inwardly, while sodium currents show little rectification, indicating voltage-dependent anion permeation.

Large-pore connexin hemichannels function as molecule transporters independently of ion conduction

The paper shows that connexin hemichannels can transport molecules independently of ion conduction, challenging the conventional view of their function.

Hippocampal Asymmetry of Regional Development and Structural Covariance in Preterm Neonates

This study compares hippocampal development in preterm and term-born neonates using MRI, finding asymmetrical structural impairments in preterm infants.

Whole-brain functional connectivity neuromarkers uncover the cognitive recovery scheme for overt hepatic encephalopathy after liver transplantation

This study identifies functional connectivity neuromarkers that reveal distinct cognitive recovery patterns in patients with overt hepatic encephalopathy after liver transplantation.