Cynthia Vierra‐Green

This study identifies distinct autoreactomes in healthy individuals based on HLA-DRB1 genotype using PhIP-Seq, showing genotype-specific autoantibody profiles and potential pathogenic autoantibodies before disease onset.

The paper generates and aligns KIR haplotypes at high resolution, defines them as 14 loci with 9 genes, and applies the alignments in software tools for haplotype annotation and genotyping.

The paper introduces an iterative feature selection method to identify predictive SNPs and their interactions in high-dimensional transplant genomic data, showing it can reduce SNP sets to less than 0.05%.

The paper uses long-read sequencing to phase and sequence sixteen KIR haplotypes from eight individuals, revealing novel structures and variants.