Author

D. A. Applewhite

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:Drosophila· 2 Assay:fluorescence / live-cell microscopy· 2 Research Focus:development & morphogenesis· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Approach:microscopy & imaging analysis· 1 Approach:statistical model· 1

Frequent Co-Authors

A. J. Harker· 1 shared D. R. Kovar· 1 shared D. Sridharan· 1 shared F. Aydin· 1 shared G. A. Voth· 1 shared H. H. Katkar· 1 shared I. Krishnamurthy· 1 shared M. E. O'Connell· 1 shared

Activity by Year

2018-2018 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

A. J. Harker

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2 papers

Recent·Most cited

Ena/VASP processive elongation is modulated by avidity on actin filaments bundled by the filopodia crosslinker fascin

A. J. Harker, H. H. Katkar, T. C. Bidone, F. Aydin, G. A. Voth, D. A. Applewhite, D. R. Kovar

This study shows Ena/VASP tetramers enhance processivity on fascin-bundled actin filaments through avidity, increasing run length with more filaments and arms.

bioRxiv · Aug 7, 2018Cell Biology

The Drosophila Cortactin Binding Protein 2 homolog, Nausicaa, regulates lamellipodial actin dynamics in a Cortactin-dependent manner.

M. E. O'Connell, D. Sridharan, T. Driscoll, I. Krishnamurthy, W. G. Perry, D. A. Applewhite

This study identifies Nausicaa as a Drosophila protein that regulates lamellipodial actin dynamics through its interaction with Cortactin.

bioRxiv · Jul 24, 2018Cell Biology