Long-term adaptation to galactose as a sole carbon source selects for mutations in nutrient signaling pathways
A. A. Martinez, A. Conboy, S. W. Buskirk, D. A. Marad, G. I. Lang
bioRxiv · May 17, 2022 · PreprintEvolutionary Biology
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D. A. Marad
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Overdominant and partially dominant mutations drive short-term adaptation in diploid yeast
D. Aggeli, D. A. Marad, X. Liu, S. W. Buskirk, S. F. Levy, G. I. Lang
The paper identifies adaptive mutations in diploid yeast by analyzing fitness effects of evolved mutations and finds that overdominant and partially dominant mutations contribute to short-term adaptation.
bioRxiv · Oct 29, 2021Evolutionary Biology
Cause and consequences of genome duplication in haploid yeast populations
K. J. Fisher, S. W. Buskirk, R. C. Vignogna, D. A. Marad, G. I. Lang
This study shows that genome duplication in haploid yeast provides immediate fitness benefits but reduces long-term adaptability.
bioRxiv · Jan 12, 2018Evolutionary Biology