S. W. Buskirk

G1-Cyclin2 (Cln2) promotes chromosome hypercondensation in eco1/ctf7 rad61 null cells during hyperthermic stress in Saccharomyces cerevisiae

The paper shows that deletion of CLN2 rescues temperature-sensitive growth in eco1 rad61 yeast mutants and affects chromosome condensation during hyperthermic stress.

Long-term adaptation to galactose as a sole carbon source selects for mutations in nutrient signaling pathways

Overdominant and partially dominant mutations drive short-term adaptation in diploid yeast

The paper identifies adaptive mutations in diploid yeast by analyzing fitness effects of evolved mutations and finds that overdominant and partially dominant mutations contribute to short-term adaptation.

Exploring a local genetic interaction network using evolutionary replay experiments

The paper uses evolutionary replay experiments to identify and validate positive genetic interactions involving KEL1 mutations in yeast, showing these interactions are not detected by loss-of-function methods.

One gene, multiple ecological strategies: a biofilm regulator is a capacitor for sustainable diversity

This study identifies parallel mutations in the rpfR gene of Burkholderia cenocepacia that enable distinct ecological strategies by regulating signaling networks and biofilm formation.

Adaptive evolution of nontransitive fitness in yeast

The paper studies nontransitive fitness evolution in yeast, showing that adaptive mutations in nuclear and viral genomes lead to nontransitive interactions where evolved clones outcompete ancestors but lose to distant ancestors.

Negative frequency-dependent selection maintains coexisting genotypes during fluctuating selection

This study shows that negative frequency-dependent selection maintains coexisting genotypes in fluctuating environments by balancing mutations in biofilm and planktonic growth regulators.

Cause and consequences of genome duplication in haploid yeast populations

This study shows that genome duplication in haploid yeast provides immediate fitness benefits but reduces long-term adaptability.

Hitchhiking and epistasis give rise to cohort dynamics in adapting populations

The paper identifies non-adaptive mutations and synergistic epistasis in yeast populations using bulk-segregant analysis of 11 lineages.