UVB mutagenesis differs in NRAS- and BRAF-mutant mouse models of melanoma
R. L. Bowman, R. C. Hennessey, D. A. Tallman, T. J. Weiss, E. R. Crawford, B. M. Murphy, A. Webb, S. Zhang, K. M. D. La Perle, C. J. Burd, R. L. Levine, A. H. Shain, C. E. Burd
This study compares UVB mutagenesis effects in NRAS- and BRAF-mutant mouse melanoma models, finding BRAF-mutant tumors have more mutations and a stronger UVB mutational signature.
bioRxiv · Dec 27, 2020 · PreprintCancer Biology