D. Barardo

The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience

The paper reanalyzes lifespan studies and finds that short-lived controls overestimate intervention efficacy, proposing a 900-day rule to assess confidence in longevity interventions.

Doubling healthy lifespan using drug synergies

This paper shows that combining drugs targeting multiple ageing pathways in C. elegans can double lifespan and improve healthspan, with potential for human applications.