Author

B. K. Kennedy

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cell Biology· 2 Cancer Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cancer & tumor microenvironment· 3 Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:metabolism & bioenergetics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

A. Asadi Shahmirzadi· 1 shared A. C. Wooldredge· 1 shared A. Pellagatti· 1 shared A. Verma· 1 shared B. Aylward· 1 shared B. Fong· 1 shared B. Harris· 1 shared B. Truong· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCell Biology

A. Asadi Shahmirzadi

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The impact of short-lived controls on the interpretation of lifespan experiments and progress in geroscience

K. K. Pabis, D. Barardo, J. Gruber, O. Sirbu, K. Selvarajoo, M. Kaeberlein, B. K. Kennedy

The paper reanalyzes lifespan studies and finds that short-lived controls overestimate intervention efficacy, proposing a 900-day rule to assess confidence in longevity interventions.

bioRxiv · Oct 8, 2023 · PreprintPhysiology

Ribosomal protein control of hematopoietic stem cell transformation through regulation of metabolism.

B. Harris, D. K. Singh, B. Truong, M. Rhodes, R. Price, S. Shinton, M. Verma, B. Aylward, S. P. Fahl, S. R. Sprinkle, S. Aminov, M. Wang, Y. Zhang, J. Perrigoue, R. Kessel, , D. L. Wiest

This study shows that reduced RPL22 expression in hematopoietic stem cells promotes leukemia by altering metabolism and increasing lipid synthesis via Lin28b.

bioRxiv · May 31, 2023Cancer Biology

Tom70-based transcriptional regulation of mitochondrial biogenesis and aging

C. Zhou, Q. Liu, C. E. Chang, A. C. Wooldredge, B. Fong, B. K. Kennedy

This study shows Tom70 regulates mitochondrial biogenesis and aging by coordinating transcription and protein import in yeast and Drosophila.

bioRxiv · Nov 23, 2021Cell Biology

Alpha-ketoglutarate, an endogenous metabolite, extends lifespan and compresses morbidity in aging mice

A. Asadi Shahmirzadi, D. Edgar, C.-Y. Liao, Y.-M. Hsu, M. Lucanic, A. Asadi Shahmirzadi, C. Wiley, R. Riley, G. Gan, C. Kuehnemann, D. Bhaumik, G. J. Lithgow, B. K. Kennedy

This study shows that alpha-ketoglutarate extends lifespan and healthspan in aging mice by reducing frailty and inflammatory factors.

bioRxiv · Oct 4, 2019Cell Biology