Author

N. S. Tolwinski

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Organism:mouse· 2 Approach:statistical model· 2 Organism:C. elegans· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A.-C. Gingras· 1 shared B. A. Liu· 1 shared C. S. Williams· 1 shared D. Barardo· 1 shared E. H. Z. Chua· 1 shared E. K. Tan· 1 shared J. Gruber· 1 shared K. C. Batchu· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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1 shared paperCell Biology

A.-C. Gingras

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3 papers

Recent·Most cited

Wnt signaling rescues amyloid beta induced stem cell loss

P. Kaur, E. H. Z. Chua, W. K. Lim, N. Harmston, N. S. Tolwinski

The paper shows that Wnt signaling rescues amyloid beta-induced stem cell loss by reducing inflammation and modulating aging-related genes.

bioRxiv · Sep 6, 2021Cell Biology

Mutated in Colorectal Cancer (MCC): a centrosomal protein that relocalizes to the ncMTOC during intestinal cell differentiation

L. B. Tomaz, B. A. Liu, S. L. M. Ong, E. K. Tan, M. M, N. S. Tolwinski, C. S. Williams, A.-C. Gingras, M. Leushacke, N. R. Dunn

This study investigates the subcellular localization of MCC in the intestinal epithelium, showing its role in centrosomal and ncMTOC dynamics during differentiation.

bioRxiv · Jul 27, 2021 · PreprintCell Biology

Doubling healthy lifespan using drug synergies

T. Dessale, K. C. Batchu, D. Barardo, L. F. Ng, V. Y. M. Lam, L. Xiao, M. R. Wenk, N. S. Tolwinski, J. Gruber

This paper shows that combining drugs targeting multiple ageing pathways in C. elegans can double lifespan and improve healthspan, with potential for human applications.

bioRxiv · Aug 1, 2017Biochemistry