Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production
E. K. Noch, L. Palma, I. Yim, D. Barnett, A. Walsh, B. Bhinder, E. Benedetti, J. Krumsiek, J. Gurvitch, S. Khwaja, O. Elemento, L. Cantley
This study shows that cysteine induces mitochondrial reductive stress in glioblastoma via hydrogen peroxide production, and NAC treatment reduces GBM cell growth.
bioRxiv · Sep 10, 2021 · PreprintCancer Biology