Author

J. Krumsiek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 4 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Organism:human· 4 Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Assay:metabolomics· 3 Approach:statistical model· 3 Research Focus:gene regulatory network inference· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1

Frequent Co-Authors

E. Benedetti· 2 shared O. Elemento· 2 shared A. A. Hakimi· 1 shared A. Ananthanarayanan· 1 shared A. Benito-Martin· 1 shared A. M. Intlekofer· 1 shared A. R. Farghli· 1 shared A. R. Savage· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCancer Biology

E. Benedetti

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Breast adipose tissue-derived extracellular vesicles from women with obesity stimulate mitochondrial-induced dysregulated tumor cell metabolism

S. Liu, A. Benito-Martin, F. A. P. Vatter, S. Z. Hanif, C. Liu, P. Bhardwaj, P. Sethupathy, A. R. Farghli, P. Piloco, P. Paik, M. Mushannen, D. M. Otterburn, L. Cohen, R. Bareja, J. Krumsiek, , K. A. Brown

This study shows that extracellular vesicles from obese women's breast adipose tissue promote mitochondrial metabolism and proliferation in ER+ breast cancer cells.

bioRxiv · Feb 8, 2023 · PreprintCancer Biology

A Multimodal Atlas of Tumor Metabolism Reveals the Architecture of Gene-Metabolite Co-regulation

E. Benedetti, E. M. Liu, C. Tang, F. Kuo, M. Buyukozkan, T. Park, J. Park, F. Correa, A. A. Hakimi, A. M. Intlekofer, J. Krumsiek, E. Reznik

The paper constructs a multimodal tumor metabolism atlas to identify gene-metabolite co-regulation patterns across cancer types.

bioRxiv · Nov 23, 2022 · PreprintCancer Biology

Gut bacteria-derived serotonin promotes immune tolerance in early life

K. Z. Sanidad, S. L. Rager, H. C. Carrow, A. Ananthanarayanan, R. Callaghan, P. Ravisankar, T. Li, A. R. Savage, J. A. Brown, M. Amir, R. Luo, F. Mardorsky Rowdo, M. L. Martin, R. B. Silver, D. Artis, , M. Y. Zeng

This study shows that neonatal gut bacteria produce serotonin, which promotes immune tolerance by inhibiting mTOR and increasing regulatory T cells.

bioRxiv · Sep 25, 2022Immunology

Cysteine induces mitochondrial reductive stress in glioblastoma through hydrogen peroxide production

E. K. Noch, L. Palma, I. Yim, D. Barnett, A. Walsh, B. Bhinder, E. Benedetti, J. Krumsiek, J. Gurvitch, S. Khwaja, O. Elemento, L. Cantley

This study shows that cysteine induces mitochondrial reductive stress in glioblastoma via hydrogen peroxide production, and NAC treatment reduces GBM cell growth.

bioRxiv · Sep 10, 2021 · PreprintCancer Biology

HSP90 facilitates oncogenic alterations of metabolism in B-cell lymphomas

M. N. Calvo-Vidal, N. Zamponi, J. Krumsiek, M. A. Stockslager, M. V. Revuelta, J. M. Phillip, R. Marullo, N. Kotlov, J. Patel, S. N. Yang, L. Yang, T. Taldone, C. Thieblemont, J. P. Leonard, P. Martin, , L. Cerchietti

This study shows HSP90 supports metabolic compartmentalization in B-cell lymphomas, and its inhibition reduces cancer metabolism.

bioRxiv · May 29, 2020 · PreprintCancer Biology