Confinement by liquid-liquid interface replicates in vivo neutrophil deformations and elicits bleb based migration
J. H. Schrope, A. Horn, K. Lazorchak, C. W. Tinnen, J. J. Stevens, M. Farooqui, J. Li, D. Bennin, T. Robertson, T. D. Juang, A. Ahmed, C. Li, A. Huttenlocher, D. Beebe
This paper introduces a liquid-liquid interface system to model in vivo neutrophil migration, finding that neutrophils use bleb-based force generation to deform barriers under confining pressures.
bioRxiv · Jun 14, 2023 · PreprintBioengineering