Author

M. Skala

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 3 Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Organism:human· 3 Assay:imaging· 3 Approach:microscopy & imaging analysis· 3 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

J.-D. Sauer· 2 shared K. Tweed· 2 shared M. Humayun· 2 shared T. Heaster· 2 shared A. Bourgois-Mochel· 1 shared A. E. Jergens· 1 shared A. Houghtaling· 1 shared A. Huttenlocher· 1 shared

Activity by Year

2018-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 11 mutual co-author links

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2 shared papersImmunology

J.-D. Sauer

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

Innate immune cell response to host-parasite interaction in a human intestinal tissue microphysiological system

M. Humayun, J. M. Ayuso, K. Y. Park, B. M. Di Genova, M. Skala, S. C. Kerr, L. Knoll, D. Beebe

The paper develops a human intestinal microphysiological system to study parasite-immune interactions, showing neutrophil and NK cell responses to Toxoplasma gondii infection.

bioRxiv · Jan 27, 2022Bioengineering

Label-free imaging for quality control of cardiomyocyte differentiation

T. Qian, T. Heaster, A. Houghtaling, K. Sun, K. Samimi, M. Skala

The paper develops a label-free imaging method to predict cardiomyocyte differentiation efficiency from hPSCs using autofluorescence and multivariate models.

bioRxiv · Jun 1, 2021Bioengineering

In vivo fluorescence lifetime imaging captures metabolic changes in macrophages during wound responses in zebrafish

V. Miskolci, K. Tweed, M. Lasarev, E. C. Britt, C. E. McDougal, A. J. Walsh, J. Fan, J.-D. Sauer, M. Skala, A. Huttenlocher

This paper uses in vivo FLIM to track metabolic changes in macrophages during wound responses in zebrafish, showing dynamic shifts in NAD(P)H and FAD redox ratios.

bioRxiv · Jun 16, 2020Immunology

Nano-Emulsion Adjuvant Enhances Cross-presentation by Lipid Body Formation Independent of Glycolysis

M. Suresh, W. Lee, B. Kingstad-Bakke, B. Paulson, A. Larsen, K. Overmyer, C. Marinaik, K. Dull, R. Toy, G. Vogel, K. Mueller, K. Tweed, A. Walsh, J. Russell, K. Saha, , K. Roy

This study shows that the nano-emulsion adjuvant Adjuplex enhances cross-presentation in dendritic cells without requiring glycolysis, relying instead on lipid body formation and ROS.

bioRxiv · May 8, 2020 · PreprintImmunology

Autofluorescence imaging of 3D tumor-macrophage microscale cultures resolves spatial and temporal dynamics of macrophage metabolism

T. Heaster, M. Humayun, J. Yu, D. J. Beebe, M. Skala

This paper uses autofluorescence imaging to study macrophage metabolism and behavior in 3D tumor models, revealing metabolic heterogeneity and migration patterns.

bioRxiv · Mar 12, 2020Bioengineering

Adult Canine Intestinal Derived Organoids: A Novel In Vitro System for Translational Research in Comparative Gastroenterology

L. Chandra, D. C. Borcherding, D. Kingsbury, T. Atherly, Y. M. Ambrosini, A. Bourgois-Mochel, W. Yuan, M. Kimber, Y. Qi, Q. Wang, M. Wannemuehler, N. M. Ellinwood, E. Snella, M. Martin, M. Skala, , K. Allenspach

This paper develops a canine intestinal organoid system to study GI diseases in dogs and humans, showing it mimics in vivo tissue and supports functional assays.

bioRxiv · Nov 9, 2018 · PreprintCell Biology