Author

D. C. Castaneda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Bioengineering· 2 Immunology· 2 Microbiology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Organism:human· 4 Assay:bulk RNA-seq· 3 Research Focus:host-pathogen & immune response· 3 Research Focus:cell type annotation· 2 Research Focus:drug response / drug discovery· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

K. Palucka· 5 shared M. Callender· 4 shared M. Schotsaert· 3 shared A. Choi· 2 shared A. Garcia-Sastre· 2 shared A. Salner· 2 shared A. Williams· 2 shared D. Chaussabel· 2 shared

Activity by Year

2023-2023 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

5 shared papersBioengineering

K. Palucka

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Species- and strain-effects in interferon, innate immunity, and barrier transcriptional response of microbiome interactions of 3D respiratory epithelial cultures

M. Horvath, R. Yang, D. C. Castaneda, M. Callender, E. Fleming, A. Voigt, R. Caldwell, J. Fachi, B. Di Luccia, Z. Scholar, P. Yu, A. Salner, M. Colonna, K. Palucka, J. Oh

The paper examines how different microbes affect host immune and barrier responses in respiratory epithelial cultures, finding that interferon variability is not linked to microbial diversity or other innate pathways.

bioRxiv · Sep 25, 2023 · PreprintMicrobiology

A 3D Printed Ventilated Perfused Lung Model Platform to Dissect the Lung's Response to Viral Infection in the Presence of Respiration

I. D. Derman, M. A. Alioglu, D. Banerjee, S. E. Holton, D. N. Klunk, M. Nagamine, S. H. A. Rizvi, C. Mikacenic, N. Celik, D. C. Castaneda, W. Prajakta, P. Chen, M. Schotsaert, M. E. Peeples, K. Palucka, , I. T. Ozbolat

This study develops a 3D printed lung model to investigate how ventilation affects viral infection and lung responses in vitro.

bioRxiv · Sep 24, 2023 · PreprintBioengineering

Protocol for primary human lung organoid-derived air-liquid interface in vitro model to study response to SARS-CoV-2

D. C. Castaneda, S. Jangra, M. Yurieva, J. Martinek, M. Callender, M. Coxe, A. Choi, J. G.-B. Diego, T.-C. Wu, F. Marches, D. Chaussabel, A. Garcia-Sastre, M. Schotsaert, A. Williams, K. Palucka

This paper presents a protocol for creating human lung organoid-derived air-liquid interface cultures to study SARS-CoV-2 infection and includes quality control and monitoring methods.

bioRxiv · Sep 10, 2023 · PreprintImmunology

Spatiotemporally organized immunomodulatory response to SARS-CoV-2 virus in primary human broncho-alveolar epithelia

D. C. Castaneda, S. Jangra, M. Yurieva, J. Martinek, M. Callender, M. Coxe, A. Choi, J. G.-B. Diego, J. Lin, T.-C. Wu, F. Marches, D. Chaussabel, P. Yu, A. Salner, G. Aucello, , K. Palucka

This study examines the spatiotemporal immune response to SARS-CoV-2 in human broncho-alveolar epithelia, finding variant-specific kinetics and spatially organized gene expression patterns.

bioRxiv · Mar 30, 2023Immunology

High-Throughput Bioprinting of the Nasal Epithelium using Patient-derived Nasal Epithelial Cells

I. D. Derman, M. Yeo, D. C. Castaneda, M. Callender, M. Horvath, Z. Mo, R. Xiong, E. Fleming, P. Chen, M. E. Peeples, K. Palucka, J. Oh, I. T. Ozbolat

This study uses 3D bioprinting to create nasal epithelium models from patient-derived cells, enabling high-throughput fabrication and recapitulating native epithelial architecture and virus infection capability.

bioRxiv · Mar 29, 2023Bioengineering