Author

D. C. Wraith

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

D. Bending· 2 shared E. K. Jennings· 2 shared N. Thawait· 2 shared T. A. E. Elliot· 2 shared A. Flores-Langarica· 1 shared D. A. J. Lecky· 1 shared G. Anderson· 1 shared J. C. Yam-Puc· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 37 mutual co-author links

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2 shared papersImmunology

D. Bending

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2 papers

Recent·Most cited

Antigen and Checkpoint Receptor Recalibration of T Cell Receptor Signal Strength

T. A. E. Elliot, E. K. Jennings, D. A. J. Lecky, N. Thawait, A. Flores-Langarica, D. C. Wraith, D. Bending

This study identifies how TCR signal strength modulates CD4+ T cell function and shows that anti-PD1 therapy increases TCR signal strength, defining a metric to stratify melanoma patient outcomes.

bioRxiv · Mar 2, 2021Immunology

Differential Nr4a1 and Nr4a3 expression discriminates tonic from activated TCR signalling events in vivo

E. K. Jennings, T. A. E. Elliot, N. Thawait, S. S. Kanabar, J. C. Yam-Puc, M. Ono, K.-M. Toellner, D. C. Wraith, G. Anderson, D. Bending

The paper identifies differential Nr4a1 and Nr4a3 expression as markers distinguishing tonic from activating TCR signalling in T cells.

bioRxiv · Jan 15, 2020Immunology