Author

D. Candinas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

D. Stroka· 3 shared D. Sanchez-Taltavull· 2 shared G. Beldi· 2 shared B. Yilmaz· 1 shared C. Mooser· 1 shared D. Pereyra· 1 shared D. Spari· 1 shared F. Jebbawi· 1 shared

Activity by Year

2018-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersImmunology

D. Stroka

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

The human vault RNA enhances tumorigenesis and chemoresistance through the lysosome

I. Ferro, J. Gavini, L. Bracher, M. Landolfo, D. Candinas, D. Stroka, N. Polacek

This study shows that vtRNA1-1 promotes tumorigenesis and chemoresistance by regulating lysosomal function through the ERK1/2-TFEB pathway.

Autophagy · May 7, 2021Peer-reviewedCell Biology

Compartmentalization of intestinal bacteria by hepatic ILC3s prevents infections after surgery

M. O. Jakob, D. Sanchez-Taltavull, B. Yilmaz, T. Malinka, C. Mooser, D. Spari, L. A. Salm, K. Freiburghaus, D. Pereyra, S. Hapfelmeier, M. Masoodi, P. Starlinger, D. Stroka, F. Tschan, D. Candinas, , G. Beldi

The paper shows that intestinal bacteria cause surgical infections and that hepatic ILC3s prevent their translocation, highlighting the role of controlled commensalism in preventing post-surgical infections.

bioRxiv · Sep 19, 2019 · PreprintImmunology

Connexin-43 dependent ATP release mediates macrophage activation during peritonitis

M. Dosch, J. Zindel, F. Jebbawi, N. Melin, D. Sanchez-Taltavull, D. Stroka, D. Candinas, G. Beldi

This study shows that Connexin-43-mediated ATP release from macrophages via TLR-2 and -4 agonists promotes sepsis severity, and inhibiting this pathway improves survival in peritonitis.

bioRxiv · Sep 23, 2018 · PreprintImmunology