Affinity-matured homotypic interactions induce spectrum of PfCSP-antibody structures that influence protection from malaria infection
G. Martin, J. L. Torres, T. Pholcharee, D. Oyen, Y. Flores-Garcia, G. Gibson, R. Moskovitz, N. Beutler, D. D. Jung, J. Copps, W.-H. Lee, G. Gonzalez-Paez, D. Emerling, R. S. MacGill, E. Locke, , A. Ward
The paper analyzes structural and functional properties of antibodies targeting PfCSP, showing how homotypic interactions and affinity maturation influence protection against malaria.
bioRxiv · Sep 20, 2022Immunology