G. Martin

The last days of Aporia crataegi (L.) in Britain: evaluating genomic erosion in an extirpated butterfly

This study compares genomic erosion in an extinct British butterfly and a stable species, finding similar heterozygosity loss despite different population sizes and suggesting inbreeding and deleterious mutations as decline indicators.

An Arabidopsis SR protein relieving ABA inhibition of seedling establishment represses ABA-responsive alternative splicing

This study identifies SR34a as an Arabidopsis SR protein that regulates alternative splicing to counteract ABA inhibition of seedling establishment.

Natural variation of immune epitopes reveals intrabacterial antagonism

The paper analyzes natural variation in immune epitopes across bacterial genomes to reveal a mechanism of intrabacterial immune evasion.

Skeletal Muscle Mitochondrial Morphology Negatively Affected by Loss of Xin

This study shows that loss of Xin in mice leads to altered mitochondrial morphology and function in skeletal muscle, without affecting mitochondrial dynamics.

Metagenomic survey of antimicrobial resistance (AMR) in Maryland surface waters differentiated by high and low human impact

The paper surveys antimicrobial resistance in Maryland surface waters, finding higher prevalence of beta-lactamase genes in high human impact areas.

Network analysis uncovers associations in the turnover of C1 molecules in a winter lake

The paper uses network analysis to study C1 molecule turnover in an ice-covered lake, revealing both known and novel microbial associations and an upward carbon flow under cold low-light conditions.

Structural basis of epitope selectivity and potent protection from malaria by PfCSP antibody L9

The paper determines the cryo-EM structure of the anti-PfCSP antibody L9, revealing its multivalent binding to NPNV repeats and the role of the light chain in affinity and protective efficacy.

Affinity-matured homotypic interactions induce spectrum of PfCSP-antibody structures that influence protection from malaria infection

The paper analyzes structural and functional properties of antibodies targeting PfCSP, showing how homotypic interactions and affinity maturation influence protection against malaria.

Whole blood transcriptome profiles of trypanotolerant and trypanosusceptible cattle highlight a differential modulation of metabolism and immune response during infection by Trypanosoma congolense

This study compares transcriptome profiles of trypanotolerant and trypanosusceptible cattle breeds during Trypanosoma congolense infection, revealing differences in immune response and metabolic regulation.

Ptr1 and ZAR1 immune receptors confer overlapping and distinct bacterial pathogen effector specificities

The paper identifies effector recognition specificities of NbPtr1 and NbZAR1 in N. benthamiana and shows their distinct and overlapping roles in detecting bacterial effectors.

A phasevarion controls multiple virulence traits, including expression of vaccine candidates, in Streptococcus pneumoniae

This study shows that the SpnIII phasevarion in S. pneumoniae affects multiple virulence traits and vaccine candidate expression, highlighting its importance in vaccine design.

Biogenic methane cycling is controlled by microbial cohorts

The paper identifies new microbial players in methane cycling by combining network analysis with cultivated model communities from a lake time-series.

BBX16 mediates the repression of seedling photomorphogenesis downstream of the GUN1-GLK1 module during retrograde signaling

This study identifies BBX16 as a novel target of GLK1 that mediates repression of seedling photomorphogenesis during chloroplast damage, revealing a molecular bifurcation mechanism in retrograde signaling.

The plant-specific SCL30a SR protein regulates ABA-dependent seed traits and salt stress tolerance during germination

This paper identifies SCL30a as a plant-specific SR protein that negatively regulates ABA signaling to control seed traits and salt stress tolerance during germination in Arabidopsis.

Survey data on European organic multi-species livestock farms

The paper surveys 102 European organic multi-species livestock farms to analyze sustainability dimensions and management practices.

A wolf in another wolf's clothing. Post-genomic regulation dictates venom profiles of medically-important cryptic kraits in India

This study identifies a new krait species and reveals venom variation among cryptic kraits in India, showing that post-genomic regulation shapes venom profiles and impacts antivenom effectiveness.

Genetics of nodulation in Aeschynomene evenia uncovers new mechanisms of the rhizobium-legume symbiosis

This study identifies key genes involved in nodulation in Aeschynomene evenia, revealing new mechanisms of rhizobium-legume symbiosis through genetic and transcriptomic analyses.

Comprehensive dataset of shotgun metagenomes from stratified freshwater lakes and ponds

The paper presents a comprehensive dataset of 267 shotgun metagenomes from 41 stratified freshwater lakes and ponds to study microbial communities and their role in carbon cycling.

Alternative splicing landscapes in Arabidopsis thaliana across tissues and stress conditions highlight major functional differences with animals

The paper analyzes alternative splicing in Arabidopsis thaliana across tissues and stress conditions, revealing distinct regulatory patterns compared to animals.

A Novel CD206 Targeting Peptide Inhibits Bleomycin Induced Pulmonary Fibrosis in Mice

This study shows that RP-832c, a CD206-targeting peptide, reduces bleomycin-induced pulmonary fibrosis in mice by decreasing fibrosis markers and inflammatory cytokines, with efficacy comparable to Pirfenidone and better than Nintedanib.

Dynamics of adaptation in an anisotropic phenotype-fitness landscape

This paper analyzes adaptation dynamics in an anisotropic phenotype-fitness landscape and shows that mean fitness trajectories may exhibit plateaus before converging, fitting empirical data from E. coli evolution experiments.

Genetic paths to evolutionary rescue and the distribution of fitness effects along them

This study uses Fisher's geometric model to show how the genetic path to evolutionary rescue shifts from single to multiple mutations as mutation rates and environmental stress increase.

Population persistence under high mutation rate: from evolutionary rescue to lethal mutagenesis

The paper studies how high mutation rates affect population persistence, showing that moderate increases can aid evolutionary rescue while larger increases lead to extinction via lethal mutagenesis.

When sinks become sources: adaptive colonization in asexuals

This study develops a framework to analyze the establishment of asexual populations in a sink habitat, showing how mutation and immigration rates influence success and timing.

Dynamics of fitness distributions in the presence of a phenotypic optimum: an integro-differential approach

The paper develops an integro-differential model to study fitness distribution dynamics under mutation and selection, showing phase transitions and validating results with simulations.

Three new genome assemblies support a rapid radiation in Musa acuminata (wild banana)

This study presents three new genome assemblies of Musa acuminata subspecies to investigate their rapid radiation and evolutionary relationships with M. balbisiana.

Evolutionary Rescue Over A Fitness Landscape

The paper models evolutionary rescue using Fisher's Geometric Model to show how stress affects adaptation and extinction risk, identifying a critical stress window for rescue probability.

Enrichment of the HIV reservoir in CD32+ CD4 T cells occurs early in blood and tissue

The paper shows HIV DNA enrichment in CD32+ CD4 T cells early in infection but finds no correlation with rebound viraemia or HIV DNA levels.

The non-stationary dynamics of fitness distributions: asexual model with epistasis and standing variation.

This paper develops a deterministic approximation framework to model asexual fitness dynamics, capturing both transient and stationary behaviors across mutation rates and epistasis models.