Author

D. D. Sears

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 1

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Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Organism:mouse· 1

Frequent Co-Authors

B. Dunkerly-Eyring· 1 shared B. O'Rourke· 1 shared C. U. Oeing· 1 shared D. A. Kass· 1 shared D. Ashok· 1 shared D. C. Sarver· 1 shared G. W. Wong· 1 shared H. Knutsdottir· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperPhysiology

B. Dunkerly-Eyring

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1 paper

Recent·Most cited

PDE9 Inhibition Activates PPARa to Stimulate Mitochondrial Fat Metabolism and Reduce Cardiometabolic Syndrome

S. Mishra, V. Hahn, N. Sadagopan, B. Dunkerly-Eyring, S. Rodriguez, D. C. Sarver, R. P. Ceddia, S. Murphy, H. Knutsdottir, V. Jani, D. Ashok, C. U. Oeing, B. O'Rourke, K. Sharma, J. Gangoiti, , D. A. Kass

This study shows PDE9 inhibition activates PPARa to enhance mitochondrial fat metabolism and reduce cardiometabolic syndrome in mice, with potential for treating obesity in men and postmenopausal women.

bioRxiv · Feb 2, 2021 · PreprintPhysiology