Structure-Activity Relationship Studies of Novel Gut-derived Lantibiotics Against Human Gut Commensals
Z. J. Zhang, C. Wu, D. Dorantes, T. Pappas, A. Sundararajan, H. Lin, E. G. Pamer, W. A. van der Donk
The paper characterizes six gut-derived nisin-like lantibiotics, evaluates their antimicrobial activity against pathogens and commensals, and identifies key residues affecting their activity.
bioRxiv · Sep 15, 2023 · PreprintBioengineering