Z. J. Zhang

Comprehensive analyses of a large human gut Bacteroidales culture collection reveal species and strain level diversity and evolution

The paper characterizes a large collection of Bacteroidales isolates from the human gut, revealing genomic and metabolomic diversity and horizontal gene transfer across species.

Exposure and resistance to lantibiotics impact microbiota composition and function

This study shows that lantibiotic resistance genes in gut bacteria affect microbiota composition and function, with implications for microbiome health and resistance strategies.

Structure-Activity Relationship Studies of Novel Gut-derived Lantibiotics Against Human Gut Commensals

The paper characterizes six gut-derived nisin-like lantibiotics, evaluates their antimicrobial activity against pathogens and commensals, and identifies key residues affecting their activity.

Quantifying the mechanical properties of yeast Candida albicans using atomic force microscopy-based force spectroscopy

The paper describes a label-free atomic force microscopy method to measure the physical properties of Candida albicans in response to host stress and antifungal drugs.

Engineered collagen-targeting therapeutics reverse lung and kidney fibrosis in mice

This study develops collagen-targeted therapeutics that reduce lung and kidney fibrosis in mice by improving drug delivery and efficacy.

Blocking antibodies against integrin-a3, integrin-aM, and integrin-aMb2 de-differentiate myofibroblasts and reverse lung and kidney fibroses in a mouse model

Blocking antibodies against integrins-3, -M, and -Mβ2 reverse lung and kidney fibrosis in a mouse model by de-differentiating myofibroblasts.

Bone Marrow-Derived AXL Tyrosine Kinase Promotes Mitogenic Crosstalk and Cardiac Allograft Vasculopathy

This study shows that bone marrow-derived AXL tyrosine kinase promotes cardiac allograft vasculopathy by enhancing immune cell accumulation and vascular smooth muscle cell proliferation.