Author

D. Doultsinos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

A. Ahmad· 1 shared A. Berg· 1 shared A. Chatziioannou· 1 shared A. Douglas· 1 shared A. Obiedat· 1 shared A. Pandit· 1 shared A. Samali· 1 shared B. Tirosh· 1 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperBioengineering

A. Ahmad

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2 papers

Recent·Most cited

Accelerating manufacturing to start large-scale supply of a new adenovirus-vectored vaccine within 100 days

C. C. Joe, R. R. Segireddy, C. Oliveira, A. Berg, Y. Li, D. Doultsinos, N. Chopra, S. Scholze, A. Ahmad, P. Nestola, J. Niemann, A. Douglas

This paper describes an accelerated manufacturing process for adenovirus-vectored vaccines, enabling large-scale supply within 100 days of pathogen identification.

bioRxiv · Dec 22, 2021 · PreprintBioengineering

Constitutive UPRER activation sustains tumor cell differentiation

D. Doultsinos, M. McMahon, K. Voutetakis, J. Obacz, R. Pineau, P.-J. Le Reste, A. Obiedat, J. Samal, J. B. Patterson, Q. Zheng, A. Samali, A. Pandit, B. Tirosh, A. Chatziioannou, E. Chevet, T. Avril

The paper shows that constitutive IRE1 activation maintains differentiation in glioblastoma cells by repressing stemness factors.

bioRxiv · Oct 22, 2019 · PreprintCancer Biology