Author

K. Voutetakis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 3 Approach:experimental assay· 3 Research Focus:gene regulatory network inference· 3 Organism:human· 3 Approach:statistical model· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Organism:mouse· 2

Frequent Co-Authors

A. Pandit· 3 shared e. chevet· 3 shared J. Samal· 3 shared R. Pineau· 3 shared T. Avril· 3 shared A. Chatziioannou· 2 shared A. Obiedat· 2 shared A. Samali· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. Pandit

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4 papers

Recent·Most cited

Molecular and functional profiling unravels targetable vulnerabilities in colorectal cancer

E. I. Vlachavas, K. Voutetakis, V. Kosmidou, S. Tsikalakis, S. Roditis, K. Pateas, R. Kim, K. Pagel, S. Wolf, G. Warsow, A. Dimitrakopoulou-Strauss, G. N. Zografos, A. Pintzas, J. Betge, O. Papadodima, S. Wiemann

This study identifies molecular vulnerabilities in colorectal cancer by analyzing MSI and MSS tumors, revealing distinct signaling pathways and potential therapeutic targets.

bioRxiv · Apr 17, 2024Cancer Biology

Local intracerebral Inhibition of IRE1 by MKC8866 sensitizes glioblastoma to irradiation/chemotherapy in vivo.

P.-J. Le Reste, R. Pineau, K. Voutetakis, J. Samal, G. Jegou, S. Lhomond, A. M. Gorman, A. Samali, J. B. Patterson, Q. Zeng, A. Pandit, M. AUBRY, N. Soriano, A. Etcheverry, J. Mosser, , e. chevet

The paper develops a novel immunocompetent GBM model to test the effect of IRE1 inhibition on treatment efficacy in vivo.

bioRxiv · Feb 20, 2020Cancer Biology

Novel IRE1-dependent proinflammatory signaling controls tumor infiltration by myeloid cells.

J. Obacz, J. Archambeau, P. J. Le Reste, R. Pineau, K. Barroso, E. Vlachavas, K. Voutetakis, T. Fainsod-Levi, A. Obiedat, Z. Granot, B. Tirosh, J. Samal, A. Pandit, J. Patterson, Q. Zheng, , e. chevet

This study identifies an IRE1-dependent proinflammatory signaling pathway in glioblastoma that promotes tumor invasion, angiogenesis, and myeloid cell infiltration.

bioRxiv · Jan 11, 2020Cancer Biology

Constitutive UPRER activation sustains tumor cell differentiation

D. Doultsinos, M. McMahon, K. Voutetakis, J. Obacz, R. Pineau, P.-J. Le Reste, A. Obiedat, J. Samal, J. B. Patterson, Q. Zheng, A. Samali, A. Pandit, B. Tirosh, A. Chatziioannou, E. Chevet, T. Avril

The paper shows that constitutive IRE1 activation maintains differentiation in glioblastoma cells by repressing stemness factors.

bioRxiv · Oct 22, 2019 · PreprintCancer Biology