AKI and CKD Worsen Outcomes in Experimental Sepsis: Creating a Reverse-translational Model of Acute Peritoneal Infection and Recovery in an Immunocompromised Host.
D. Floyd, J. R. Colbert, S. B. Furgeson, J. R. Montford
This study shows that mice with acute kidney injury (AKI) or chronic kidney disease (CKD) have worse outcomes from sepsis compared to controls, with AKI causing more severe and earlier mortality.
bioRxiv · Mar 1, 2023 · PreprintImmunology