Author

A. Hopke

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

D. Irimia· 3 shared M. K. Mansour· 2 shared A. Amir· 1 shared A. K. Scherer· 1 shared A. Viens· 1 shared B. Villavicencio· 1 shared C. Godfrey· 1 shared C. Rhee· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersCell Biology

D. Irimia

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Self-extinguishing relay waves enable homeostaticcontrol of human neutrophil swarming

J. Strickland, D. Pan, C. Godfrey, J. S. Kim, A. Hopke, M. Degrange, B. Villavicencio, M. K. Mansour, C. S. Zerbe, D. Irimia, A. Amir, O. D. Weiner

The paper identifies a self-extinguishing relay wave mechanism in human neutrophils that controls swarming and recruitment levels through an NADPH-oxidase-based feedback loop.

bioRxiv · Jun 27, 2023Cell Biology

Predestined neutrophil heterogeneity in homeostasis varies in transcriptional and phenotypic response to Candida

A. K. Scherer, A. Hopke, S. Xu, A. Viens, N. J. Alexander, K. D. Timmer, D. Archambault, D. Floyd, N. J. Atallah, C. Rhee, M. Cetinbas, D. Scadden, D. Irimia, D. B. Sykes, R. I. Sadreyev, M. K. Mansour

The paper shows that clonal neutrophil progenitors have predestined transcriptional and epigenetic heterogeneity that influences their response to Candida infections.

bioRxiv · Nov 1, 2022 · PreprintImmunology

Chemotaxis and swarming in differentiated HL60 neutrophil-like cells

K. A. Babatunde, X. Wang, A. Hopke, P.-Y. Mantel, D. Irimia

This study shows that DMSO-differentiated HL-60 cells exhibit chemotaxis and swarming toward zymosan particles but with less organized movement and smaller swarms compared to primary neutrophils.

bioRxiv · Sep 3, 2019Cell Biology