Author

C. Rhee

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:development & morphogenesis· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1

Frequent Co-Authors

D. Scadden· 2 shared A. Araujo· 1 shared A. E. Boitano· 1 shared A. Earl· 1 shared A. Hopke· 1 shared A. K. Scherer· 1 shared A. Viens· 1 shared B.-K. Lee· 1 shared

Activity by Year

2022-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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2 shared papersImmunology

D. Scadden

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Lymphoid origin of a lineage of intrinsically activated plasmacytoid dendritic cell in mice and humans

A. Araujo, J. D. Dekker, K. Garrison, Z. Su, C. Rhee, Z. Hu, B.-K. Lee, D. Osorio, J. Lee, V. R. Iyer, L. I. R. Ehrlich, G. Georgiou, G. C. Ippolito, S. Yi, H. O. Tucker

The paper identifies a novel plasmacytoid dendritic cell lineage in mice and humans derived from common lymphoid progenitors, characterized by unique gene expression and functional properties.

bioRxiv · Jun 13, 2024Immunology

CD45-antibody-drug conjugate clears tissue resident myeloid cells from their niches enabling therapeutic adoptive cell transfer

K. Gustafsson, C. Rhee, V. Frodermann, E. W. Scadden, Y. Iwamoto, R. Palchaudhuri, S. L. Hyzy, A. E. Boitano, M. Nahrendorf, D. Scadden

This study shows that anti-CD45-ADC clears tissue-resident myeloid cells, enabling efficient replacement with donor cells and reducing atherosclerotic plaque burden.

bioRxiv · Sep 5, 2023 · PreprintImmunology

Cell of origin epigenetic priming determines susceptibility to Tet2 mutation

G. Schiroli, V. K. Kartha, F. M. Duarte, T. A. Kristiansen, C. Mayerhofer, R. Shrestha, A. Earl, Y. Hu, T. Tay, C. Rhee, J. Buenrostro, D. T. Scadden

The paper shows that the epigenetic state of the cell of origin influences susceptibility to Tet2 mutation, with Sox4 promoting dedifferentiation and increased clonal output in hematopoietic stem cells.

bioRxiv · Sep 4, 2023 · PreprintCancer Biology

Predestined neutrophil heterogeneity in homeostasis varies in transcriptional and phenotypic response to Candida

A. K. Scherer, A. Hopke, S. Xu, A. Viens, N. J. Alexander, K. D. Timmer, D. Archambault, D. Floyd, N. J. Atallah, C. Rhee, M. Cetinbas, D. Scadden, D. Irimia, D. B. Sykes, R. I. Sadreyev, M. K. Mansour

The paper shows that clonal neutrophil progenitors have predestined transcriptional and epigenetic heterogeneity that influences their response to Candida infections.

bioRxiv · Nov 1, 2022 · PreprintImmunology