Author

D. G. Olson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:bacteria (other)· 1 Organism:C. elegans· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Research Focus:protein folding & dynamics· 1 Approach:statistical model· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. A. Lanahan· 1 shared B. Knott· 1 shared E. E. Romero· 1 shared J. N. Gruber· 1 shared K. Zakowicz· 1 shared L. R. Lynd· 1 shared L. Tian· 1 shared L.-M. Joubert· 1 shared

Activity by Year

2021-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperBioengineering

A. A. Lanahan

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2 papers

Recent·Most cited

Structural characterization and dynamics of AdhE ultrastructures from Clostridium thermocellum: A containment strategy for toxic intermediates.

S. J. Ziegler, B. Knott, J. N. Gruber, N. N. Hengge, Q. Xu, D. G. Olson, E. E. Romero, L.-M. Joubert, Y. J. Bomble

This study uses cryo-EM and molecular dynamics to characterize AdhE ultrastructures in C. thermocellum, revealing a containment strategy for toxic intermediates in ethanol synthesis.

bioRxiv · Feb 16, 2024Biophysics

A single nucleotide change in the polC DNA polymerase III in Clostridium thermocellum is sufficient to create a hypermutator phenotype

A. A. Lanahan, K. Zakowicz, L. Tian, D. G. Olson, L. R. Lynd

The paper introduces a C669Y mutation in polC of C. thermocellum, resulting in a 30-fold increase in mutation rate and a hypermutator phenotype.

bioRxiv · Jul 30, 2021Bioengineering