Author

D. Gahtory

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Javed· 1 shared A. M. J. J. Bonvin· 1 shared D. W. Zijlmans· 1 shared E. J. A. Veldhuizen· 1 shared E. P. M. Timmermans-Sprang· 1 shared F. van der Krift· 1 shared G. J. Strous· 1 shared J. A. Mol· 1 shared

Activity by Year

2023-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. Javed

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1 paper

Recent·Most cited

A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance

F. van der Krift, D. W. Zijlmans, R. Shukla, A. Javed, P. I. Koukos, L. L. E. Schwarz, E. P. M. Timmermans-Sprang, P. E. M. Maas, D. Gahtory, M. van den Nieuwboer, J. A. Mol, G. J. Strous, A. M. J. J. Bonvin, E. J. A. Veldhuizen, M. van der Stelt, , M. M. Maurice

This study identifies a novel antifolate, C1, that overcomes methotrexate resistance by targeting FPGS-deficient cells through DHFR inhibition.

bioRxiv · Feb 26, 2023Biochemistry