Author

M. van der Stelt

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1 Assay:organoid / primary culture· 1

Frequent Co-Authors

A. Dong· 1 shared A. English· 1 shared A. Javed· 1 shared A. Kaptein· 1 shared A. M. J. J. Bonvin· 1 shared B. B. Land· 1 shared B. I. Florea· 1 shared D. Gahtory· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

A. Dong

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

A novel antifolate suppresses growth of FPGS-deficient cells and overcomes methotrexate resistance

F. van der Krift, D. W. Zijlmans, R. Shukla, A. Javed, P. I. Koukos, L. L. E. Schwarz, E. P. M. Timmermans-Sprang, P. E. M. Maas, D. Gahtory, M. van den Nieuwboer, J. A. Mol, G. J. Strous, A. M. J. J. Bonvin, E. J. A. Veldhuizen, M. van der Stelt, , M. M. Maurice

This study identifies a novel antifolate, C1, that overcomes methotrexate resistance by targeting FPGS-deficient cells through DHFR inhibition.

bioRxiv · Feb 26, 2023Biochemistry

ABHD6 selectively controls metabotropic-dependent increases in 2-AG production

S. Singh, D. Sarroza, A. English, D. Whittington, A. Dong, M. van der Stelt, Y. Li, L. Zweifel, M. R. Bruchas, B. B. Land, N. Stella

The paper shows ABHD6 selectively regulates metabotropic-dependent 2-AG production via DAGL and calcium, unlike ionotropic-dependent increases.

bioRxiv · May 18, 2022 · PreprintCell Biology

Chemical genetics strategy to profile kinase target engagement reveals role of FES in neutrophil phagocytosis via SYK activation

T. van der Wel, R. Hilhorst, H. den Dulk, T. van den Hooven, N. M. Prins, J. A. P. M. Wijnakker, B. I. Florea, E. B. Lenselink, G. J. P. van Westen, R. Ruijtenbeek, H. S. Overkleeft, A. Kaptein, T. Barf, M. van der Stelt

The paper uses a chemical genetics strategy to study FES kinase target engagement in human cells, revealing its role in neutrophil phagocytosis via SYK activation.

bioRxiv · Nov 13, 2019Physiology