Author

D. Gonzalez-Martinez

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

J. Guan· 2 shared L. J. Bugaj· 2 shared A. A. Pal· 1 shared A. Idris· 1 shared A. Tulpule· 1 shared B. Huang· 1 shared D. Rae· 1 shared E. Brackhahn· 1 shared

Activity by Year

2022-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 30 mutual co-author links

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2 shared papersBioengineering

J. Guan

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Author profile →

2 papers

Recent·Most cited

Simple visualization of submicroscopic protein clusters with a phase-separation-based fluorescent reporter.

T. R. Mumford, D. Rae, E. Brackhahn, A. Idris, D. Gonzalez-Martinez, A. A. Pal, M. C. Chung, J. Guan, E. Rhoades, L. J. Bugaj

This paper introduces CluMPS, a fluorescent reporter that detects and amplifies submicroscopic protein clusters, enabling visualization of small oligomers and endogenous protein assemblies.

bioRxiv · Jul 13, 2022Bioengineering

Oncogenic protein condensates suppress growth factor perception and modulate drug tolerance

D. Gonzalez-Martinez, L. Roth, T. Mumford, J. Guan, B. Huang, A. Tulpule, T. G. Bivona, L. J. Bugaj

This study shows that oncogenic protein condensates suppress RTK signaling and modulate drug tolerance in ALK-driven cancers by sequestering adapter proteins and enabling paracrine survival signals.

bioRxiv · Feb 2, 2022Cancer Biology