L. Roth

Mitochondrial reverse electron transport in myeloid cells perpetuates neuroinflammation

The paper identifies mitochondrial reverse electron transport in myeloid cells as a driver of neuroinflammation and shows that blocking it protects the CNS in disease models.

Temporal resolution trumps spectral resolution in UAV-based monitoring of canopy senescence dynamics

This study compares multispectral and RGB sensors on UAVs for monitoring wheat canopy senescence, finding that frequent measurements are more effective than high spectral resolution.

From neglecting to including cultivar-specific per se temperature responses: Extending the concept of thermal time for plant development modeling

This study challenges the assumption of species-level temperature responses in plant development models by showing cultivar-specific temperature responses significantly affect phenology and other stressor interactions.

Image-based phenomic prediction can provide valuable decision support in wheat breeding

This study uses image-based phenotyping to predict wheat yield and protein content, showing moderate accuracy and insights into genotype-environment interactions.

High-throughput field phenotyping reveals that selection in breeding has affected the phenology and temperature response of wheat in the stem elongation phase

This study uses high-throughput field phenotyping to show that wheat breeding since 1970 has altered phenology and temperature response in the stem elongation phase, aiding climate adaptation.

Oncogenic protein condensates suppress growth factor perception and modulate drug tolerance

This study shows that oncogenic protein condensates suppress RTK signaling and modulate drug tolerance in ALK-driven cancers by sequestering adapter proteins and enabling paracrine survival signals.

Phenomics data processing: Extracting dose-response curve parameters from high-resolution temperature courses and repeated field-based wheat height measurements

This study extracts temperature response parameters from field-based wheat height measurements using an asymptotic model, showing high precision for base temperature and growth rate but reduced accuracy with changing cardinal temperatures.

Phenomics data processing: A plot-level model for repeated measurements to extract the timing of key stages and quantities at defined time points

The paper develops a plot-level model for processing repeated high-throughput field phenotyping data to extract key stages and quantities, showing that P-splines and QMER are more robust than percentiles for timing extraction.

Molecular determinants of Yellow Fever Virus pathogenicity in Syrian Golden Hamsters: one mutation away from virulence

This study identifies key mutations in Yellow Fever Virus that enhance virulence in Syrian Golden Hamsters by analyzing their effects on disease symptoms and replication.