Author

D. Grewal

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 4

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Research Focus:differential expression· 4 Organism:human· 4 Assay:scRNA-seq· 3 Approach:statistical model· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:gene regulatory network inference· 2

Frequent Co-Authors

A. McPherson· 3 shared A. W. Zhang· 3 shared D. Lai· 3 shared M. J. Williams· 3 shared N. Ceglia· 3 shared N. Rusk· 3 shared S. Aparicio· 3 shared S. P. Shah· 3 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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3 shared papersCancer Biology

A. McPherson

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Author profile →

4 papers

Recent·Most cited

Luminal breast epithelial cells from wildtype and BRCA mutation carriers harbor copy number alterations commonly associated with breast cancer

M. J. Williams, M. U. Oliphant, V. Au, C. Liu, C. Baril, C. O'Flanagan, D. Lai, S. Beatty, M. Van Vliet, J. C. Liu, L. O'Connor, W. L. Goh, A. Pollaci, A. C. Weiner, D. Grewal, , S. Aparicio

The paper analyzes copy number alterations in breast epithelial cells from BRCA mutation carriers and wildtype individuals, finding lineage-specific CNAs that mirror cancer genomes.

bioRxiv · May 1, 2024 · PreprintCancer Biology

Immune and malignant cell phenotypes of ovarian cancer are determined by distinct mutational processes

I. Vazquez-Garcia, F. Uhlitz, N. Ceglia, J. L. P. Lim, M. Wu, N. Mohibullah, A. E. B. Ruiz, K. M. Boehm, V. Bojilova, C. J. Fong, T. Funnell, D. Grewal, E. Havasov, S. Leung, A. Pasha, , Nikolovsk

This study identifies distinct immune and malignant cell phenotypes in ovarian cancer linked to specific mutational processes and anatomic sites.

bioRxiv · Aug 24, 2021Cancer Biology

The impact of mutational processes on structural genomic plasticity in cancer cells

T. Funnell, C. H. O'Flanagan, M. J. Williams, A. McPherson, S. McKinney, F. Kabeer, H. Lee, T. Masud, P. Eirew, D. Yap, A. W. Zhang, J. L. P. Lim, B. Wang, J. Brimhall, J. Biele, , S. Aparicio

The paper analyzes structural genomic variations in cancer cells to understand how mutational processes influence cell-to-cell genomic diversity and tumor evolution.

bioRxiv · Jun 3, 2021 · PreprintCancer Biology

Single cell fitness landscapes induced by genetic and pharmacologic perturbations in cancer

S. Salehi, F. Kabeer, N. Ceglia, M. Andronescu, M. Williams, K. R. Campbell, T. Masud, B. Wang, J. Biele, J. Brimhall, J. Ting, A. W. Zhang, C. H. OFlanagan, F. Dorri, N. Rusk, , S. P. Shah

This study develops a quantitative fitness model to analyze clonal dynamics in cancer under genetic and pharmacologic perturbations, revealing how mutations and drug resistance shape tumor evolution.

bioRxiv · May 8, 2020Cancer Biology