D. Gupta

HA Nanocarriers Mediate HepG2 Vaccine Induction of hGM-CSF Gene Antitumor effect study

This study evaluates the anti-tumor effect of HA nanoparticle-mediated hGM-CSF gene-transfected HepG2 cell vaccine in vitro, showing enhanced PBMC proliferation, cytotoxicity, and IFN-γ secretion compared to controls.

Preparation of Artesunate mPEG-PLGA Nanoparticles and Its Application to K562 Apoptosis of cells

This paper prepares artesunate-loaded mPEG-PLGA nanoparticles and shows they inhibit K562 cell proliferation and induce apoptosis more effectively than free artesunate.

Targeting study of HepG2 hepatoma cells in vitro by drug-loaded pectin-based nanoparticles

This study develops pectin-based nanoparticles loaded with 5-FU to target HepG2 cells, showing enhanced uptake and proliferation inhibition compared to free 5-FU.

Preparation and in vitro release of fluorouracil polylactide glycolide-polyethylene glycol monomethyl ether nanoparticles

The paper describes the preparation of fluorouracil-loaded PLGA-mPEG nanoparticles and evaluates their in vitro release characteristics.

mTORC1 Restricts Hepatitis C Virus Replication Through ULK1-mediated Suppression of miR-122 and Facilitates Post-replication Events

This study shows mTORC1 suppresses HCV replication via ULK1-mediated reduction of miR-122 and supports post-replication events, with ULK1 depletion increasing miR-122 levels.