Author

D. H. de Groot

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 4 Research Focus:cell signaling & trafficking· 1 Organism:E. coli· 1 Approach:experimental assay· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

F. J. Bruggeman· 3 shared A. J. Tjalma· 1 shared A. M. Berkvens· 1 shared A. Papachristodoulou· 1 shared C. C. M. Schulte· 1 shared E. van Nimwegen· 1 shared G. Saalbach· 1 shared J. H. van Heerden· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 13 mutual co-author links

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3 shared papersMicrobiology

F. J. Bruggeman

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Growth consequences of the inhomogeneous organization of the bacterial cytoplasm

J. H. van Heerden, A. M. Berkvens, D. H. de Groot, F. J. Bruggeman

This paper shows that inhomogeneous cytoplasm organization in E. coli causes growth rate perturbations during cell division, with smaller cells compensating differently than larger ones.

bioRxiv · Apr 18, 2023 · PreprintMicrobiology

Coupling phenotype stability to growth rate overcomes limitations of bet-hedging strategies

D. H. de Groot, A. J. Tjalma, F. J. Bruggeman, E. van Nimwegen

This study shows that growth rate dependent stability (GRDS) overcomes the limitations of bet-hedging strategies in microbes by allowing adaptive exploration and stability based on growth rate.

bioRxiv · Apr 12, 2022 · PreprintEvolutionary Biology

Metabolic constraints on nitrogen fixation by rhizobia in legume nodules

C. C. M. Schulte, K. Borah, R. Wheatley, J. Terpolilli, G. Saalbach, N. Crang, D. H. de Groot, R. G. Ratcliffe, N. J. Kruger, A. Papachristodoulou, P. S. Poole

The paper models bacteroid metabolism in legume nodules to show how oxygen levels and dicarboxylate catabolism affect nitrogen fixation and redox balance.

bioRxiv · Feb 16, 2021 · PreprintMicrobiology

Cell fate determination by Lamarckian molecule-inheritance and chance

F. J. Bruggeman, J. Schouten, D. H. de Groot, R. Planque

The paper develops a theory to explain cellular heterogeneity by considering stochastic ancestral events in isogenic cell populations, showing that copy-number noise is unavoidable due to cell division stochasticity.

bioRxiv · Apr 24, 2019 · PreprintBiophysics