Author

D. H. Wyllie

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 3

Signature Assays, Organisms & Methods

Click to filter · or open tag

Assay:whole-genome sequencing· 3 Research Focus:differential expression· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:variant calling· 2 Research Focus:batch correction / integration· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

A. S. Walker· 3 shared D. W. Crook· 3 shared E. G. Smith· 3 shared E. Robinson· 2 shared A. A. Votintseva· 1 shared A. Ajileye· 1 shared A. Chatterjee· 1 shared C. del Ojo Elias· 1 shared

Activity by Year

2016-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersMicrobiology

A. S. Walker

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

MicrobiologyJournal of InfectionPeer-reviewedJul 1, 2022

M. tuberculosis microvariation is common and is associated with transmission: analysis of three years prospective universal sequencing in England

D. H. Wyllie, T. Do, R. Myers…·E. G. Smith

This study identifies microvariation in M. tuberculosis strains using sequencing data from England, finding that mixed infections are associated with increased tuberculosis transmission.

DOI 10.1016/j.jinf.2022.05.011

humanwhole-genome sequencing

𝕏 PostBluesky

MicrobiologybioRxivJun 12, 2018

Identifying mixed Mycobacterium tuberculosis infection and laboratory cross-contamination during Mycobacterial sequencing programs

D. H. Wyllie, E. Robinson, T. E. A. Peto…·A. S. Walker

The paper develops metrics to detect mixed Mycobacterium tuberculosis infections and cross-contamination in sequencing data from tuberculosis diagnostic labs.

DOI 10.1128/jcm.00923-18

whole-genome sequencingstatistical model

𝕏 PostBluesky

MicrobiologybioRxivDec 19, 2016

Same-day diagnostic and surveillance data for tuberculosis via whole genome sequencing of direct respiratory samples.

A. A. Votintseva, P. Bradley, L. Pankhurst…·Z. Iqbal

This paper develops a low-cost WGS method for TB diagnosis and surveillance using direct respiratory samples, achieving rapid results with high concordance with reference labs.

DOI 10.1128/jcm.02483-16

humanwhole-genome sequencing

𝕏 PostBluesky