D. J. Lew

Mechanism of commitment to a mating partner in Saccharomyces cerevisiae

This study investigates how yeast cells commit to mating partners despite varying pheromone levels, finding that steep gradients near polarity sites trap them in place, enabling sexual selection for higher pheromone production.

Exploratory polarization facilitates mating partner selection in Saccharomyces cerevisiae

The paper shows yeast cells use mobile polarity sites to explore pheromone gradients, stabilizing only when they detect high pheromone levels, facilitating mating partner selection.

How cells determine the number of polarity sites

The paper shows that cells can switch from competition to equalization among polarity sites, determining the number of polarity sites through regulatory mechanisms.

Mating in wild yeast: variable interest in sex after spore germination

This study examines mating behavior in wild yeast strains after spore germination, finding variable mating propensity linked to pheromone production differences.

Principles that govern competition or co-existence in Rho-GTPase driven polarization

The paper derives a saturation rule that predicts whether Rho-GTPase systems will produce uni-polar or multi-polar outcomes based on competition timescales.