Author
A. W. McClure
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
Click to filter author papersSignature Assays, Organisms & Methods
Click to filter · or open tagActivity by Year
2018-2021 · peak 4/yrCo-Author Collaboration Network
10 top collaborators · 45 mutual co-author links5 papers
Recent·Most cited
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp14/nsp10 Exoribonuclease
C. Basier, S. Basu, R. Beale, A. P. Bertolin, B. Canal, J. F. Curran, T. D. Deegan, J. F. Diffley, L. S. Drury, R. Fujisawa, M. Howell, K. Labib, A. W. McClure, J. Milligan, E. Roberts, , J. Zeng
This study identifies patulin and aurintricarboxylic acid as inhibitors of SARS-CoV-2 nsp14 exoribonuclease, showing antiviral activity in cell culture.
bioRxiv · Apr 7, 2021Biochemistry
Identifying SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of Nsp15 Endoribonuclease
R. Beale, A. P. Bertolin, B. Canal, T. D. Deegan, J. F. Diffley, L. S. Drury, R. Fujisawa, M. Howell, K. Labib, A. W. McClure, R. Ulferts, F. Weissmann, M. Wu, J. Zeng
This study screens for small molecule inhibitors of SARS-CoV-2 nsp15 endoribonuclease and identifies NSC95397 as an in vitro inhibitor, though its antiviral efficacy remains to be determined.
bioRxiv · Apr 7, 2021Biochemistry
Identification of SARS-CoV-2 Antiviral Compounds by Screening for Small Molecule Inhibitors of the nsp14 RNA Cap Methyltransferase
C. Basier, S. Basu, R. Beale, B. Canal, V. H. Cowling, J. F. Curran, T. D. Deegan, J. F. Diffley, L. S. Drury, R. Fujisawa, M. Howell, K. Labib, C. T. Lim, T. Mak, A. W. McClure, , T. U. Zeisner
This study identifies four small molecule inhibitors of SARS-CoV-2 nsp14 RNA cap methyltransferase, with three showing synergy with remdesivir in antiviral assays.
bioRxiv · Apr 7, 2021Bioengineering
Mating in wild yeast: variable interest in sex after spore germination
A. W. McClure, K. C. Jacobs, T. R. Zyla, D. J. Lew
This study examines mating behavior in wild yeast strains after spore germination, finding variable mating propensity linked to pheromone production differences.
bioRxiv · Jul 1, 2018Cell Biology