Author

D. J. Schaer

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 3

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:clustering· 1 Approach:deep learning· 1 Organism:mouse· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. Rudiger· 2 shared C. Cervia· 2 shared J. Nilsson· 2 shared L. C. Huber· 2 shared M. E. Raeber· 2 shared O. Boyman· 2 shared S. Adamo· 2 shared Y. Zurbuchen· 2 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersImmunology

A. Rudiger

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Author profile →

3 papers

Recent·Most cited

Heme-stress activated NRF2 signaling skews fate trajectories of bone marrow cells from dendritic cells towards red pulp-like macrophages

F. Vallelian, R. M. Buzzi, M. Pfefferle, A. Yalamanoglu, A. Wassmer, T. Gentinetta, K. Hansen, R. Humar, N. Schulthess, D. J. Schaer

This study shows heme-stress activates NRF2 signaling in bone marrow cells, shifting their differentiation from dendritic cells to red pulp-like macrophages, contributing to immunodeficiency in hemolytic diseases.

bioRxiv · Jul 29, 2021Immunology

A distinct innate immune signature marks progression from mild to severe COVID-19

S. Chevrier, Y. Zurbuchen, C. Cervia, S. Adamo, M. E. Raeber, N. de Souza, S. Sivapatham, A. Jacobs, E. Bächli, A. Rudiger, M. Stüssi-Helbling, L. C. Huber, D. J. Schaer, J. Nilsson, O. Boyman, B. Bodenmiller

The paper identifies an innate immune signature associated with progression from mild to severe COVID-19 using mass cytometry and proteomics.

bioRxiv · Aug 4, 2020Immunology

Systemic and mucosal antibody secretion specific to SARS-CoV-2 during mild versus severe COVID-19

C. Cervia, J. Nilsson, Y. Zurbuchen, A. Valaperti, J. Schreiner, A. Wolfensberger, M. E. Raeber, S. Adamo, M. Emmenegger, S. Hasler, P. P. Bosshard, E. De Cecco, E. Baechli, A. Rudiger, M. Stuessi-Helbling, , O. Boyman

This study compares SARS-CoV-2-specific antibody responses in mild and severe COVID-19 patients and healthcare workers, finding higher systemic IgA and IgG in severe cases and mucosal IgA in asymptomatic exposed individuals.

bioRxiv · May 21, 2020Immunology