IL-2 immunotherapy rescues irradiation-induced T cell exhaustion in vivo
C. S. M. Yong, I. Telarovic, L. Gregor, M. E. Raeber, M. Pruschy, O. Boyman
This study shows that timed CD25-biased IL-2 immunotherapy after RT enhances anti-tumor effects by promoting CD8+ T cell expansion and reducing exhaustion.
bioRxiv · Jan 29, 2024 · PreprintImmunology