Spatially resolved molecular analysis of host response to medical device implantation using the 3D OrbiSIMS
W. Suvannapruk, L. E. Fisher, J. C. Luckett, M. K. Edney, A. M. Kotowska, D.-H. Kim, D. J. Scurr, A. Ghaemmaghami, M. R. Alexander
The paper uses 3D OrbiSIMS to analyze metabolite signatures in tissue around implanted medical devices, linking them to pro- or anti-inflammatory immune responses.
bioRxiv · Aug 18, 2023Bioengineering