Molecular engineering improves antigen quality and enables integrated manufacturing of a trivalent subunit vaccine candidate for rotavirus
N. C. Dalvie, J. R. Brady, L. E. Crowell, M. K. Tracey, A. M. Biedermann, K. Kaur, J. M. Hickey, D. L. Kristensen, A. Bonnyman, S. A. Rodriguez-Aponte, C. A. Whittaker, M. Bok, C. Vega, T. Mukhopadhyay, S. B. Joshi, , J. C. Love
The paper engineers subunit antigens to improve vaccine manufacturing by reducing variants and enabling single-process production of a trivalent rotavirus vaccine.
bioRxiv · Nov 20, 2020Bioengineering