Author

D. Leshchiner

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

A. Peraino· 1 shared A. T. Nishimoto· 1 shared B. Chen· 1 shared B. Jana· 1 shared B. Sundaresh· 1 shared C. Lawson· 1 shared C. O. Rock· 1 shared D. Chesla· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperCell Biology

A. Peraino

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2 papers

Recent·Most cited

Bulk RNA-Sequencing of small airway cell cultures from IPF and post-COVID lung fibrosis patients illustrates disease signatures and differential responses to TGF-β1 treatment

K. Uhl, S. Paithankar, D. Leshchiner, T. Jager, M. Abdelgied, K. Tripp, A. Peraino, M. Kakazu, C. Lawson, D. Chesla, J. Prokop, B. Chen, E. Murphy, R. Girgis, X. Li

This study uses bulk RNA-sequencing to compare gene expression in small airway cells from IPF and post-COVID fibrosis patients, revealing disease-specific genetic signatures and differential responses to TGF-β1 treatment.

bioRxiv · Mar 1, 2023 · PreprintCell Biology

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance.

D. Leshchiner, F. Rosconi, B. Sundaresh, E. Rudmann, L. M. Nieto Ramirez, A. T. Nishimoto, S. Wood, B. Jana, N. Bujan, K. Li, J. Gao, M. Frank, S. M. Reeve, R. E. Lee, C. O. Rock, , T. van Opijnen

This study creates a genome-wide atlas of antibiotic susceptibility targets in Streptococcus pneumoniae, identifying a 'tolerome' that influences resistance and highlights its evolutionary significance.

bioRxiv · Jan 26, 2022Microbiology