A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance.
D. Leshchiner, F. Rosconi, B. Sundaresh, E. Rudmann, L. M. Nieto Ramirez, A. T. Nishimoto, S. Wood, B. Jana, N. Bujan, K. Li, J. Gao, M. Frank, S. M. Reeve, R. E. Lee, C. O. Rock, , T. van Opijnen
This study creates a genome-wide atlas of antibiotic susceptibility targets in Streptococcus pneumoniae, identifying a 'tolerome' that influences resistance and highlights its evolutionary significance.
bioRxiv · Jan 26, 2022Microbiology