S. Wood

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance.

This study creates a genome-wide atlas of antibiotic susceptibility targets in Streptococcus pneumoniae, identifying a 'tolerome' that influences resistance and highlights its evolutionary significance.

Accuracy and precision of citizen scientist animal counts from drone imagery

This study evaluates the accuracy and precision of citizen science counts of seals and sea lions from drone imagery, finding low proportional error but slow processing times and underestimation issues.

Improved 7 Tesla Transmit Field Homogeneity with Reduced Electromagnetic Power Deposition Using Coupled Tic Tac Toe Antennas

This paper optimizes a 7T MRI RF head coil design to improve magnetic field homogeneity and reduce power deposition through electromagnetic simulations and in-vivo validation.

Nitric oxide prevents aortic valve calcification by S-nitrosylation of USP9X to activate NOTCH signaling

The paper shows nitric oxide prevents aortic valve calcification by S-nitrosylating USP9X to activate NOTCH signaling in porcine valve cells and mice.

Antibiotic hypersensitivity signatures identify targets for attack in the Acinetobacter baumannii cell envelope

This study identifies antibiotic hypersensitivity signatures in A. baumannii to discover new targets for attacking the pathogen's cell envelope.

Transcriptome Dynamics Reveals Progressive Transition from Effector to Memory in CD4+ T cells.

This study uses single-cell RNA-seq and ATAC-seq to show a progressive transition from effector to memory CD4+ T cells during Plasmodium infection, with linear pathways and memory-associated gene expression.

The landscape of intrinsic and evolved fluoroquinolone resistance in Acinetobacter baumannii includes suppression of drug-induced prophage replication

This paper identifies mutations that alter fluoroquinolone sensitivity in Acinetobacter baumannii and shows that preferential Topo IV poisoning leads to prophage induction and SOS response activation.

droplet-Tn-Seq combines microfluidics with Tn-Seq identifying complex single-cell phenotypes

droplet-Tn-Seq uses microfluidics to encapsulate transposon mutants individually, enabling single-cell analysis of bacterial fitness while retaining Tn-Seq advantages.

Transparent Titanium Dioxide Nanotubes: Processing, Characterization, and Application in Establishing Cellular Response Mechanisms

This paper develops a transparent TiO2 nanotube platform for live-cell imaging to study cellular response mechanisms to nanostructured surfaces.

First data-driven approach to using individual cattle weights to estimate mean adult dairy cattle weight in the UK

This paper estimates the mean adult dairy cattle weight in the UK using on-farm data, finding an average of 620 kg, higher than the commonly cited 600 kg.