R. E. Lee

Reduced male fertility of an Antarctic mite following extreme heat stress could prompt localized population declines

This study shows that extreme heat stress reduces male fertility in Antarctic mites, potentially leading to population declines.

Viral Airway Injury Promotes Cell Engraftment in an In Vitro Model of Cystic Fibrosis Cell Therapy

This study shows that viral airway injury enhances cell engraftment in an in vitro CF model by creating conditions that favor non-CF cell integration and functional CFTR recovery.

A genome-wide atlas of antibiotic susceptibility targets and pathways to tolerance.

This study creates a genome-wide atlas of antibiotic susceptibility targets in Streptococcus pneumoniae, identifying a 'tolerome' that influences resistance and highlights its evolutionary significance.

Robust W1282X-CFTR rescue by a small molecule GSPT1 degrader

The paper develops Bmi-1/hTERT cell lines to model CFTR variants and shows that CC-90009 partially rescues W1282X-CFTR function while affecting sodium channel activity.

Rapid stress hardening in the Antarctic midge improves male fertility by increasing courtship success and preventing the decline of accessory gland proteins following cold exposure

This study shows that rapid hardening in Antarctic midges improves male fertility by enhancing courtship success and maintaining accessory gland protein expression after cold exposure.

SARS-CoV-2 D614G Variant Exhibits Enhanced Replication ex vivo and Earlier Transmission in vivo

This study shows the SARS-CoV-2 D614G variant replicates more efficiently and transmits faster in hamsters than the wildtype virus.

Brief exposure to a diverse range of environmental stress enhances stress tolerance in the polyextremophilic Antarctic midge, Belgica antarctica

The paper shows that brief exposure to diverse environmental stresses enhances stress tolerance in Antarctic midge larvae.